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NIH3D

TRICHLOROETHYLENE

PubChem 6575
was used by NIH 3D workflows to automatically generate models for
zenway9
Created:
9/14/16
Submitted:
9/14/16
Published:
9/14/16

3DPX-003712

Licensing:

Public Domain
157
7
Version 1

Category

Small Molecules
Small Molecules
Description

Most of the trichloroethylene used in the United States is released into the atmosphere from industrial degreasing operations. Acute (short-term) and chronic (long-term) inhalation exposure to trichloroethylene can affect the human central nervous system (CNS), with symptoms such as dizziness, headaches, confusion, euphoria, facial numbness, and weakness. Liver, kidney, immunological, endocrine, and developmental effects have also been reported in humans. A recent analysis of available epidemiological studies reports trichloroethylene exposure to be associated with several types of cancers in humans, especially kidney, liver, cervix, and lymphatic system. Animal studies have reported increases in lung, liver, kidney, and testicular tumors and lymphoma. The Agency is currently reassessing the cancer classification of trichloroethylene.