Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

National Institute of Allergy and Infectious Disease
NIH 3D
FAQsBioArt

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock () or https:// means you’ve safely connected to the .gov website. Share sensitive information only on official, secure websites.

NIH3D

Buprenorphine

PubChem 644073
was used by NIH 3D workflows to automatically generate models for
ryosakai
Created:
8/25/16
Submitted:
10/6/26
Published:
10/6/26
ball-and-stick, color, print caution
644073-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-003645

NIH 3D DOI:

https://doi.org/10.60705/3dpx/3645.3

Licensing:

Public Domain
How to cite this NIH 3D entry
549
32
Version 3

Category

Small Molecules
Small Molecules
Description
Buprenorphine is a morphinane alkaloid that is 7,8-dihydromorphine 6-O-methyl ether in which positions 6 and 14 are joined by a -CH2CH2- bridge, one of the hydrogens of the N-methyl group is substituted by cyclopropyl, and a hydrogen at position 7 is substituted by a 2-hydroxy-3,3-dimethylbutan-2-yl group. It is highly effective for the treatment of opioid use disorder and is also increasingly being used in the treatment of chronic pain. It has a role as a kappa-opioid receptor antagonist, an opioid analgesic, a mu-opioid receptor agonist and a delta-opioid receptor antagonist.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=644073&width=400&height=400