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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Pyrimethamine

PubChem 4993
was used by NIH 3D workflows to automatically generate models for
kwhutchins
Created:
7/25/16
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
4993-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball and stick, print cautionsticks, not intended for 3D printingsticks, not intended for 3D printingsticks, print cautionspace-filled, print cautionsticks, print cautionball and stick, print cautionspace-filled, print caution
3DPX-003492

NIH 3D DOI:

https://doi.org/10.60705/3dpx/3492.2

Licensing:

Public Domain
How to cite this NIH 3D entry
30
3
Version 2

Category

Small Molecules
Small Molecules
Description
Pyrimethamine is an aminopyrimidine that is pyrimidine-2,4-diamine which is substituted at position 5 by a p-chlorophenyl group and at position 6 by an ethyl group. It is a folic acid antagonist used as an antimalarial or with a sulfonamide to treat toxoplasmosis. It has a role as an antimalarial, an EC 1.5.1.3 (dihydrofolate reductase) inhibitor and an antiprotozoal drug. It is an aminopyrimidine and a member of monochlorobenzenes.
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=4993&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=4993&width=400&height=400