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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Paclitaxel; (Taxol)

Generated by NIH 3D workflows using data provided by
rej5y7
Created:
3/23/16
Submitted:
3/6/23
Published:
3/6/23
ball and stick, print caution
10368587-bas-color-print_NIH3DAtoms shown as ball-and-stick with standard colors. 3D printable, with caution, using certain 3D printers.

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3DPX-003114

Licensing:

Public Domain
How to cite this NIH 3D entry
645
94
Version 2

Category

Small Molecules
Small Molecules
Description

Paclitaxel is a compound extracted from the Pacific yew tree Taxus brevifolia with antineoplastic activity. Paclitaxel binds to tubulin and inhibits the disassembly of microtubules, thereby resulting in the inhibition of cell division. This agent also induces apoptosis by binding to and blocking the function of the apoptosis inhibitor protein Bcl-2 (B-cell Leukemia 2). 

Source Data Details