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NIH3D

Carbidopa

PubChem 34359
was used by NIH 3D workflows to automatically generate models for
Meghan McCarthy
Created:
3/15/16
Submitted:
3/6/23
Published:
3/6/23

Select an image below to view

3DPX-003075

Licensing:

Public Domain
68
2
Version 2

Category

Small Molecules
Small Molecules
Description

Carbidopa (anhydrous) is 3-(3,4-Dihydroxyphenyl)propanoic acid in which the hydrogens alpha- to the carboxyl group are substituted by hydrazinyl and methyl groups (S-configuration). Carbidopa is a dopa decarboxylase inhibitor, so prevents conversion of levodopa to dopamine. It has no antiparkinson activity by itself, but is used (commonly as its hydrate) in the management of Parkinson's disease to reduce peripheral adverse effects of levodopa. It has a role as an EC 4.1.1.28 (aromatic-L-amino-acid decarboxylase) inhibitor, an antiparkinson drug and a dopaminergic agent. It is a member of hydrazines, a monocarboxylic acid and a member of catechols.
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=34359&width=400&height=400
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=34359&width=400&height=400