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National Institute of Allergy and Infectious Disease
NIH 3D
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NIH3D

Donepezil

PubChem 3152
was used by NIH 3D workflows to automatically generate models for
Meghan McCarthy
Created:
8/7/15
Submitted:
10/6/26
Published:
10/6/26
ball-and-stick, color, print caution
3152-bas-color-print_cautionAtoms shown as ball-and-stick (geometry appears faceted on screen; apply smooth normals in Blender or similar to improve visualization; generally smooth when 3D printed) with standard colors. 3D printable, with caution, using certain 3D printers.

Select an image below to view

ball-and-stick, color, print cautionball-and-stick, no color, NIH 3D repairedthin sticks, colorthin sticks, no colorthick sticks, color, print cautionthick sticks, no color, NIH 3D repairedspace-filled, color, print cautionspace-filled, no color, NIH 3D repaired

Learn more about NIH 3D workflow outputs

3DPX-001765

NIH 3D DOI:

https://doi.org/10.60705/3dpx/1765.3

Licensing:

Public Domain
How to cite this NIH 3D entry
511
33
Version 3

Category

Small Molecules
Small Molecules
Description
Donepezil is a racemate comprising equimolar amounts of (R)- and (S)-donepezil. A centrally acting reversible acetylcholinesterase inhibitor, its main therapeutic use is in the treatment of Alzheimer's disease where it is used to increase cortical acetylcholine. It has a role as an EC 3.1.1.8 (cholinesterase) inhibitor, an EC 3.1.1.7 (acetylcholinesterase) inhibitor and a nootropic agent. It contains a (S)-donepezil and a (R)-donepezil. It is a conjugate base of a donepezil (1+).
Source Data Details
https://pubchem.ncbi.nlm.nih.gov/image/imagefly.cgi?cid=3152&width=400&height=400