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NIH3D

Ubiquitin

Created by
aarono
Created:
6/25/14
Submitted:
10/5/26
Published:
10/5/26

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Learn more about NIH 3D workflow outputs

3DPX-000365

Licensing:

CC-BY-SA
358
15
Version 3

Category

Biomacromolecules
Biomacromolecules
Description

"Ubiquitin is a small (8.5 kDa) regulatory protein that has been found in almost all tissues (ubiquitously) of eukaryotic organisms. Ubiquitination is a post translational modification (an addition to a protein after it has been made) where ubiquitin is attached to a substrate protein." 
http://en.wikipedia.org/wiki/Ubiquitin 
The addition of ubiquitin to proteins can signal for their degradation via the proteasome. 
This model is based on Human erythrocytic ubiquitin. The C-terminal glycine residue, conjugated to the lysine residues of target proteins, is represented as spheres. Model based on the Protein Data Bank entry 1ubq: 
http://www.rcsb.org/pdb/explore/explore.do?structureId=1ubq 
Model created using VMD: 
http://www.ks.uiuc.edu/Research/vmd/